In vitro Lipolysis and Leptin Production of Elephant Seal Blubber Using Precision-Cut Adipose Tissue Slices
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چکیده
منابع مشابه
Assessment of immunotoxicity using precision-cut tissue slices
1.When the immune system encounters incoming infectious agents, this generally leads to immunity. The evoked immune response is usually robust, but can be severely perturbed by potentially harmful environmental agents such as chemicals, pharmaceuticals and allergens. 2.Immunosuppression, hypersensitivity and autoimmunity may occur due to changed immune activity. Evaluation of the immunotoxic po...
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Following the initial confirmation of the existence of leptin in humans by Friedman and his colleagues (Zhang et al. I994), many publications rapidly appeared concerning all aspects of its regulation and action. However, only a small proportion of these have addressed the in vivo physiology of leptin in man. It is apparent that the main determinant of leptin concentrations in both animals and h...
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Brown adipose tissue (BAT) plays an important role in thermoregulation in species living in cold environments, given heat can be generated from its chemical energy reserves. Here we investigate the existence of BAT in blubber in four species of delphinoid cetacean, the Pacific white-sided and bottlenose dolphins, Lagenorhynchus obliquidens and Tursiops truncates, and Dall's and harbour porpoise...
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Alcohol abuse results in liver injury, but investigations into the mechanism(s) for this injury have been hampered by the lack of appropriate in vitro culture models in which to conduct in depth and specific studies. In order to overcome these shortcomings, we have developed the use of precision-cut liver slices (PCLS) as an in vitro culture model in which to investigate how ethanol causes alco...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2020
ISSN: 1664-042X
DOI: 10.3389/fphys.2020.615784